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| 1852 |
| | | Queen Victoria opens the new Houses of Parliament, designed by Charles Barry and Augustus Welby Pugin | |
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| 1852 |
| | | The Crystal Palace is dismantled in Hyde Park, to be re-erected south of the river Thames at Sydenham | |
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| 1852 |
| | | Scottish physicist William Thomson formulates the second law of thermodynamics, concerning the transfer of heat within a closed system | |
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| 1852 |
| | | Lord Aberdeen, leader of the 'Peelite' minority of the Conservative party, forms a new coalition government with the Liberals | |
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| 1852 |
| | | London physician Peter Mark Roget publishes his dictionary of synonyms, the Thesaurus of English Words and Phrases | |
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| 1853 |
| | | The hypodermic syringe with a plunger is simultaneously developed in France and in Scotland | |
|  | Alexander Wood's hypodermic syringe
Wellcome Library, London
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| 1854 |
| | | English physician John Snow proves that cholera is spread by infected water (from a pump in London's Broad Street) | |
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| 1854 |
| | | Britain and France enter the war between Turkey and Russia, on the Turkish side | |
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| 1854 |
| | | A London editor decides to send a reporter, William Howard Russell ('Russell of The Times'), to the Crimean front | |
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| 1854 |
| | | Florence Nightingale, responding to reports of horrors in the Crimea, sets sail with a party of twenty-eight nurses | |
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